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DNA Mysteries And Miracles


These unpaired chromosomes came to be known as the sex cells and coincided with Mendel's observation that his pea plant sperm cells carried a single copy of factors (DNA Watson). Across the Atlantic Ocean in Germany, another scientist by the name of Theodor Boveri had independently come up with the same conclusion as Sutton (DNA Watson). In a strange twist of fate, Thomas Morgan (who actually set out to disprove the Sutton-Boveri theory), ended up reasserting and even surpassing the original theory. Using the Drosophila melanogaster, or fruit fly, Morgan demonstrated the idea of "sex-linkage", (where particular characteristics are disproportionately represented in one sex), and the notion of what we call recombination (the breaking and re-forming of chromosomes during the production of sperm and egg cells) (DNA Watson). It was now apparent; Mendel's genes were located on the chromosomes and Darwin's variability in nature was found through recombination.
             It would take almost all the first half of the twentieth century for the next major breakthrough to occur. Debates over whether it was proteins or DNA that were the bearers of "genetic instruction" for human life, (even though DNA was located exclusively ON the chromosomes), kept the latter out of the picture until 1944 (DNA Watson). Experiments by Avery, MacLeod, and McCarty documented without a doubt that DNA held the code. Based on the work of a British scientist (in which a heat-treated form of Pneumococcus and an innocuous strain of the same bacteria combined to return the first to it's lethal state), Avery et al. systematically destroyed individual parts of the bacteria's machinery through the use of enzymes to determine what made the transformation possible (DNA Watson). The answer finally came when they subjected the heat-treated form to the DNase, a DNA-destroying enzyme; all reproduction of the lethal Pneumococcus strain ceased (DNA Watson).


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