A blastocyst consists of two parts, a hollow sphere of cells, and the inner cell mass (ICM). The outer layer of cells will eventually form the placenta and other tissues that are needed for the support and development of the fetus. The ICM will form all of the tissues of the human body. The cells extracted from the ICM are pluripotent; they are able to give rise to many, but not all cell types necessary for fetal development (for example, they are able to give rise to fetal tissues, but not placental tissue). It is this pluripotent stem cell that is currently under investigation for medical use. .
The pluripotent cells then further specialize into another type of stem cell, a multipotent stem cell. Multipotent stem cells give rise to cells that have a particular function. For example, blood stem cells give rise to red blood cells, white blood cells and platelets. Skin stem cells give rise to the different types of skin cells. These stem cells, hold the possibilities of slowing the aging process, curing diseases, genetic defects and blindness, growing replacement body parts, and determining the causes of Down Syndrome and related birth defects.
Several methods exist for extracting stem cells. But only a few provide any real hope of future therapeutic use. The most readily available sources to extract stem cells from are aborted fetal matter, or the blastocyst. However, clinical uses of stem cells from these sources are limited. When they are injected into a patient, chances of their immune system rejecting the cells are high, due to their difference in genetic make up. So why not use stem cells directly from the patient? Researchers have found very few adult stem cells. They have been used with some success. For example human stem cells extracted from the brains of aborted human fetuses greatly enhanced the cognitive ability of 24 month old rats (equivalent of an 80+ year old human) (Laino).