1. Ecstasy
Experiment 1 Synaptic transmission (In Vitro methods).
The isolated chick biventer-cervicis muscle- The mechanism of action of depolarising and non depolarising blockers.
Introduction.
This experiment was an investigation into the mechanism by which depolarising and non depolarising blockers have their effect on the nicotinic receptors of the neuromuscular junction. The nicotinic receptor of the neuromuscular junction is an ionotropic, ligand gated receptor which when stimulated by acetylcholine (or another agonist e.g. Nicotine) opens and allows the passage of sodium ions through the channel into the intracellular environment whilst potassium ions are simultaneously passing through the channel to the extracellular environment. This causes a depolarisation leading to an action potential. This via the influx of calcium from voltage gated calcium channels causes muscle contraction. .
This experiment is concerned with the blocking of the nicotinic receptor, and therefore decreasing muscle contractility, by the mechanisms of depolarising and non depolarising blockers and investigating the results to allow us to distinguish between these two kinds of blockers.
The basic action of these (without going into too much detail) is that a depolarising blocker basically works by stimulating the nicotinic receptor so much that the receptor becomes desensitized to any agonist action. This mechanism differs from the action of non depolarising blockers greatly. They have their effect by competing with acetylcholine for receptor sites. They are antagonists, so they have no effect on the receptor other that to deprive the active site to an agonist. The experiment is to see if there is a difference in the results from both that would allow the nature of the drugs used to be used.
Method.
Without proceeding into too much detail the procedure for the experiment is as follows: The biventer-cervicis muscles of a 2-12 day year old chick were taken and set up in an organ bath by methods discussed in the practical procedure guide.
Ecstasy It is estimated that 94.1 million Americans of the age 12 or older has used an illicit drug at least once in their lifetimes, one of those drugs being Ecstasy. Ecstasy (a.k.a. ... One of the most common settings for the use of Ecstasy is at a rave (a type of dance club). ... Ecstasy is also said to inhibit or restrain an orgasm and prevent an erection in some men. ... Because the quality of street ecstasy is notoriously poor, having the ability to at least narrow down the possible contents can help reduce the risks associated with the use of street ecstasy. ...
Ecstasy It is estimated that 94.1 million Americans of the age 12 or older has used an illicit drug at least once in their lifetimes, one of those drugs being Ecstasy. ... One of the most common setting for the use of Ecstasy is at a rave (a type of dance club). ... Ecstasy is also said to inhibit or restrain an orgasm and prevent an erection in some men. ... Because the quality of street ecstasy is notoriously poor, having the ability to at least narrow down the possible contents can help reduce the risks associated with the use of street ecstasy. ... Although tolerance levels increa...
And recently, one of the most popular drugs being Ecstasy. ... The active ingredient in Ecstasy is the drug called MDMA. ... But recently, ecstasy has been reaching frat houses and high schools. ... This goes to show just how prevalent ecstasy is. ... Ecstasy is so popular because it appears to have few negative consequences and users seem to have control over themselves while on ecstasy. ...
Ecstasy: Invading the Youth The year is 2000. ... Ecstasy is the catch 22, if you will. ... "Despite the danger, ecstasy still has great word of mouth. ... So, adding ecstasy to the list of "don'ts- would suffice. ... What does a straight-and-narrow gym teacher know about ecstasy? ...
In this research paper I will address the following: the history of Ecstasy, Ecstasy's positive effects on the body while in use, the side effect Ecstasy has on the body while in us, and reasons why Ecstasy use has risen among college students. I also interviewed 3 people (2 of whom have done Ecstasy, and 1 who has not) and got feedback from them about the rise of Ecstasy use in college. ... Ecstasy's Positive Effect On The Body While In Use What Ecstasy does is very simple, yet difficult to describe. ... I asked a woman named Poanni who has done Ecstasy before if she thinks that...
Coincident with this has been the rise in the use of Ecstasy. ... Little wonder that Ecstasy use increased so rapidly; the downside was yet to come. ... Gilbert and Pearson go so far as to describe Ecstasy as a technology in itself. ... Ecstasy is the only recreational psychoactive substance to be equally used by both men and women. ... Described thus far the experience of the combined effects of Ecstasy sounds truly Utopian. ...
Ecstasy Ecstasy, illegal in almost every country around the world has been found to still be one of the biggest markets in the illegal drug industry. ... History of Ecstasy The word ecstasy is derived from the Greek language and defined as state of exaltation in which the self is transcended. ... Ecstasy is MDMA, or 3,4-Methylenedioxymethamphetamine. ... Ecstasy has many effects on the body. ... Legality of ecstasy Today ecstasy is found almost all around the world. ...
The long-term effects of Ecstasy are still unclear. ... "Club Drugs More Agony Than Ecstasy for Young Patients." ... "Drug Culture Panel Urges "Less Hysteria" Over Ecstasy." ... The risks of taking Ecstasy can be severe. ... As a step in the fight against Ecstasy, the government and law enforcement agencies have enforced anti-Ecstasy laws. ...
Ecstasy is Methylene Dioxymethamphetamine, often abbreviated as MDMA. ... Ecstasy alone makes people biased towards ecstasy without even doing the research necessary to judge it. ... Before ecstasy was called MDMA, it was known as MDA. ... Ecstasy replaced cocaine as the drug of choice. ... Ecstasy produces a euphoric, comfortable, relaxed state of mind. ...