1. Beta Globin Locus
Abstract Understanding the control of the developmentally regulated switch of gene expression within the beta-globin locus is a main focus of research today. ... The expression of the genes on the beta-globin locus is controlled by a series of both general and tissue-restricted transcription factors. In addition, recent models of globin switching have focused on competition and cooperation between enhancers, promoters, and the locus control region (Bulger and Groudine, 1999). ... This element, the locus control region (LCR), promotes full levels of expression of the five genes on the beta...
- Word Count: 1387
- Approx Pages: 6
- Grade Level: Undergraduate