Macbeth throughout the play murders several people, these murders are motivated mainly by two things: Macbeth himself, who he is and what he implies, and Lady Macbeth, who manipulates Macbeth's weak personality to accomplish the assassinations. Macbeths excessive desire to obtain more than he could bear or/and deserve, takes him initially to kill the King, which later brings a sentiment of fear, because if the king died he would be king of Scotland. When King Duncan names Macbeth Thane of Cawdor showing gratitude for everything he had done, Macbeth begins to become a nemesis, yearning to be more than just the Thane of Crawdor. A sense of power, and thirst of power, grew on Macbeth's head until these arose as his acts of treason and murder. On the other side Lady Macbeth is who encourages him to act this way, killing the king and Duncan. Macbeth is a person who would do everything in order to make his wife happy and who is very manageable, allowing his wife to manipulate him into committing murder. Another thing that encourages Macbeth to act this way is the prophecy of the witches; this prediction makes Macbeth's "hunger- for power greater, which at the hand of the other motivations lead to the murders. .
Once Macbeth has Murder his first victim, King Duncan, each and every murder afterwards is virtually "easier- to commit. When Macbeth kills the king he is giving his soul, his life, to evil. This bad dead "sold him- and will make him unable to get rid of his conscience's voice; he knows that what he did is in opposition to nature and what is natural is that he will not rest in peace because of his acts. According to this way of thinking Macbeth thinks that the only way to rest in peace is to get rid of every natural thing within him. He would do this by committing more evil deeds ( murdering), which is not natural, he wanted to "kill- every natural aspect in him so his conscience would leave him in peace; as I said before conscience y a natural, but if every natural thing is vanished, conscience will also be missing.