The aggression that arrives from BPD can often not be controlled and comes out in bursts of destruction of property, assault, domestic violence, self-injury, suicide, substance abuse and the potential of suicide. There has been much research that has shown females have a three to one ratio of BPD over men. Now, in recent studies it has come to the conclusion that there are equal chances of men and women having this disorder, the difference is how it affects makes them act. Men with BPD tend to have higher explosive temperament issues and substance abuse while females are more likely to suffer from eating disorders, mood disorders, anxiety or PTSD. The Corticostriatal pathways have been implicated to motivate goal directed behaviors, habit learning, economic and social decision-making. The Striatum is activated by primary and secondary reinforcement including maternal or romantic suggestions of socially rewarding cues. Deregulation of Basal and Corticostriatal has been associated with causing aggressive behaviors in Schizophrenia, unipolar, bipolar disorder, OCD and alcoholism. A study was done between 38 BPD patients and 36 healthy patients with no degree of psychiatric disorders found, the study was finding a homogeneous group of subjects clinically significant impulsive aggression relating to IED-R. The study that was done is called Point Subtraction Aggression Paradigm (PSAP), which is a study that was used to provoke aggressive behavior. The study is designed as a computer game for the patients, where you only need to click one of three buttons. A,B, or C, the point of the game is the collect enough points to win money. By pressing A you win more points, pressing B you are subtracting points from the other players and C is protecting yourself from having the other person take away your points. The results of the experiment were males selected the more aggressive way to play by pressing B more than the female BPD patients.
