Each and every day tens of thousands of people worldwide suffer from a disease known as sickle-cell anemia. This autosomal recessive disease causes pain and agony for everyone in its path. In sickle-cell patients the hemoglobin is defective, causing pain and ultimately can damage tissue. This disease is a complexity of overlaying symptoms, that can be excruciating for the victim.
Red blood cells carry oxygen throughout the body to nourish tissues and sustain life. When the cells are healthy they resemble small inner tubes. This unique shape allows the cells to serve many functions. The large surface area allows more oxygen to be absorbed, and enhances flexibility to squeeze when necessary through capillaries. Oxygen is carried within the red blood cells by hemoglobin. Sickle-cell disease is caused by a genetic defect in the hemoglobin molecules. The disease is triggered when red blood cells become deprived of oxygen, therefore resulting in sickle-shaped, rigid, and sticky blood cells that are unable to squeeze through capillaries. The blood flow is blocked, depriving tissues and organs of oxygen. .
Effects and severity of the disease range vastly from patient to patient. The abnormal shape of the cell, causes water and potassium loss. This loss will later result in dehydration. Sickle cells also have a shorter life span than the normal red blood cells. The crescent shaped cells are destroyed many times so rapidly the body cannot keep up. The red blood cell count drops, which results in anemia. This rapid destroying process is what gave the disease its name.
"As medical progress has increased the life span of children with the sickle-cell disease, older patients are now facing medical problems- (Web, MD). "The hallmark of sickle-cell anemia is a group of devastating symptoms known collectively as a sickle-cell crisis" (Web, MD). Sickle-cell crises are episodes of pain that occur with different severities.
Sickle Cell Anemia Thesis: After examining my disease of Sickle Cell Anemia I have found out new information about the disease I. What is Sickle Cell? ... What causes Sickle Cell? ... What may come from Sickle Cell Sickle Cell Anemia Sickle Cell Anemia is a disease found commonly in African-Americans. Sickle Cell is a form of hemolytic anemia which is an anemia that breaks down the red blood cells. ...
Abstract This research project will focus on the study of sickle cell anemia. ... It will focus on what sickle cell anemia is, how a person may obtain or transfer this disease, and the function of cells carrying sickle cell anemia. ... Sickle Cell Anemia/ Sickle Cell Disease Definition "Sickle cell anemia (SCA) is an inherited form of anemia- a condition in which there is not enough healthy red blood cells to carry adequate oxygen throughout your body" (Mayo Clinic Staff). ... There is currently no available cure for sickle cell anemia. ... Sickle cell anemia is a painful disease an...
Sickle Cell Anemia Sickle Cell Anemia is a an inherited, chronic disease in which the red blood cells, normally disc-shaped, become crescent shaped. ... The symtoms of Sickle Cell Anemia include fatigue, breathlessness, cough, rapid heart rate and delayed growth. ... Also, prenatal diagnosis is now possible for couples at risk of producing a child with sickle cell anemia. ... However regular heath maintenance is critical for people with sickle cell anemia. ... In fact, in the past 30 years, the life expectancy of people with sickle cell anemia has increased. ...
Sickle cell anemia is inherited and can be expressed as either sickle cell trait when the gene is derived from only one parent, or as a full blown anemia, when both parents catty the recessive gene. (1) The genetic defect that causes sickle cell anemia affects hemoglobin, which is a component of red blood cells. ... People with sickle cell anemia have a type of abnormal hemoglobin called hemoglobin S. ... Caucasians also have sickle cell disease or trait. (5) In the United States, sickle cell anemia is most common among African Americans. ... The painful "sickle crisis" is the most dram...
Sickle cell anemia is inherited and can be expressed as either sickle cell trait when the gene is derived from only one parent, or as a full blown anemia, when both parents catty the recessive gene. (1) The genetic defect that causes sickle cell anemia affects hemoglobin, which is a component of red blood cells. ... People with sickle cell anemia have a type of abnormal hemoglobin called hemoglobin S. ... Caucasians also have sickle cell disease or trait. (5) In the United States, sickle cell anemia is most common among African Americans. ... The painful "sickle crisis" is the most dram...
The sickled blood cells can lead to anemia. ... Another common symptom is Anemia. Anemia causes shortness of breath, fatigue and delayed growth and development for children. This is why most people call sickle cell disease sickle cell anemia. ... Other names for sickle cell disease include Hemoglobin s disease, SCD, sickle cell disorders, sickling disorder due to hemoglobin S, and sickle cell anemia. ...
The genetic disorder I was told to research was the Sickle Cell Disease. ... The Sickle Cell Disease is an inherited disease. ... Fortunately only 20% of all red blood cells become Sickle Cells; the sickle cells have a shorter life span; and most blood cells go through the capillaries before becoming sickle-shaped. ... The other symptoms of Sickle Cells include: strokes, increased infections, early gallstones, yellow discoloring of eyes and skin, low blood cell counts (anemia), and delayed growth. ... Droxia, the prescription form of hydroxyurea, was approved by the FDA in 1998 and is now avai...
The alpha subunit is normal in people with sickle cell anemia. ... If both B-globin genes code for the sickle protein, the person has sickle cell anemia. ... -If one parent has sickle cell trait (HbAS) and the other does not carry the sickle hemoglobin at all (HbAA) then none of the children will have sickle cell anemia. ... There is a one in two (50%) chance that any given child will get the sickle cell trait.  -If one parent has sickle cell trait (HbAS) and the other has sickle cell anemia (HbSS) there is a one in two (50%) chance that any given child will get sickle cell t...
