Blood testing involves looking for specific antibodies within the patient's blood, which are made by the body to fight the HIV virus. People found to possess HIV antibodies, and thus suffer from HIV, are known as "HIV Positive". There are no clear and definite diagnostic symptoms, but early clinical signs may include fevers, headaches, fatigue and muscle aches. On average, it takes over ten years for symptoms to develop. HIV infects the T-helper cells (lymphocytes) and other white blood cells, resulting in their destruction. There is a variation between the viruses infecting each person (due to the nature and behaviour of a "retrovirus"), and this is the reason why the development of an appropriate vaccine has been so difficult. .
Patients who are HIV-Positive are diagnosed with AIDS when their "CD4 count" indicates that there are less than 200 CD4+ cells per cubic millimetre of blood. The CD4 cells are the cells otherwise known as "T-Helper cells". A reduction in the number of circulating CD4+ cells, results in a corresponding reduction in the number of white blood cells, and the immune system becomes significantly weaker. As time goes on, AIDS reduces the number of white cells and the infected person becomes immune deficient, as they have no effective immune system. This means they are very susceptible to bacteria and viruses. As they are unable to fight against further infection by bacteria and viruses, illnesses will inevitably result in death.
There is no cure (or vaccine) for HIV or AIDS at present. Researchers all over the world are working to develop drugs against AIDS. The most promising drug is one called AZT (Zidovudine). AZT prevents reverse transcriptase making DNA from RNA, which thus prevent HIV from making viral DNA from viral RNA so it is not inserted into the host cells DNA to form the provirus. These drugs, however, do not cure the condition; they simply extend the life of AIDS patients, thereby improving their quality of life.