The Medo - Persian Empire superseded the Babylon Empire in 539 B., approximately fifty to sixty years after Nebuchadnezzar's dream, and Daniel's interpretation. In my mind after reading and researching all the information, the Medo - Persian Empire was a kingdom with great prophetic value before and during the Intertestament Period.
In the book, "How Shall We tell The Children" Chamberlin describes Nebuchadnezzar's visions as the entire history and age of the gentiles. This is because it has been said that "the four Empires where that of gentile descent." He goes on to compare the revelations of chapters two and seven as being given to the gentiles to be understood from their perspective and interpretations." (e.g. Edward Chamberlin) This what I question, If the gentiles where to look at the interpretations from their perspective; did they know that the Medo - Persian Empire was in fact of great prophetic value long before Nebuchadnezzar's dream, and Daniel's interpretation? .
Lets us go back, if the Medo- Persian Empire. It did not rise until some fifty to sixty years after Nebuchadnezzar's dream, and Daniel's interpretation, that would mean that the Kingdom had great prophetic value before the visions. A prophet named Isaiah had already prophesied about Cyrus. The bible tells us that Isaiah prophesied about Cyrus and called him by name some two hundred years before Cyrus was born (Isaiah 44:28; 45:1). What was his significance and who was he really? Cyrus was the said "Gods shepherd", during the conversation that Isaiah had with God he was told that Cyrus would "say rebuild Jerusalem, and it would be rebuilt and he would say lay the foundations of the temple and they would be laid".
The scriptures in the Bible seem to tell us that Daniel was Hebrew prophet, and a well renowned man known for his integrity. He is called upon many of times, for his gift of interpretation. Daniel had visions that were of prophetic value, given to him by God.