After Powhatan's death in 1618, the relationship between the Virginia settlers and the Native Americans disintegrated. The Powhatan Confederacy took charge, and in 1622, the confederacy murdered 347 Englishmen/women in the worst uprising since Jamestown was founded. Within two years the Virginia Company was bankrupt, so King James I made Virginia a royal colony supervised by the crown (Monk 14). Not exactly what Powhatan would have done, is it?.
Massasoit was a much more serious case. Massasoit was the chief of the Wampanoags, and it was he who signed the peace agreement with Governor John Carver and the Pilgrims. He was a very powerful man who made sure there was nothing but peace between them. All of that changed however, when he died around 1656. After that, Massasoit's son Wamsutta (or Alexander) had continued peaceful relations with Plymouth, although it was clear that his faith had begun to yield. After Wamsutta's death, which some Wampanoags thought happened by poisoning of the English, his so Metacom (Philip) came into power. Metacom continued peace with Plymouth, but it was clear by his actions that he had lost all confidence in the English, thus meaning that he did not consider them allies anymore. Consequently this led to King Phillip's War.
The expansion of the colonies had also played an important part in the breakdown between nthe whites and the Native Americans. Without the founding of the Wessagusset Colony, the relationship between the Pilgrims and the Europeans would have never become so strained, and if the Massachusetts Bay colong hadn't arrived, Plymouth would have never been taken over.
In 1622, Thomas Weston sent a group of colonists to settle Massachusetts Bay, and it was named the Wessagussett Colony. The colonists were mostly rowdy Englishmen, and the rough behavior of the new colonists disturbed relations. The Indians complained to the Pilgrims about the abuse they endured, the Pilgrims felt that they owed loyalty to their fellow countrymen.