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Basics of Tissue Engineering

 

            
             Imagine a day when people with heart failure can be remedied with implanted "neo-organs " composed of heart cells and plastic fibers or when insulin dependent diabetics can forget their insulin injections because they have an incipient semisynthetic supersession pancreas. Due to shortage of transplantable organs many people will die. There is hope now with the more preponderant insight into the structural and behavioral characteristics of living tissues because researchers have commenced to investigate the possibility of designing and engendering tissues. The science of this engineering will be prosperous in the near future.
             Definition.
             Tissue Engineering is the study of the growth of new connective tissues, or organs, from cells and a collagen scaffold to produce a fully functional organ for implantation back into the donor host. Tissue engineering is the creation of synthetic or semisynthetic tissue that can be used instead of human tissue in surgery. Different kinds of tissue have been developed or are currently being researched, including skin, bone, cartilage, cornea, and spinal tissue. The technique will allow organs to be grown from implantation rather than transplantation. The starting point for any tissue-engineered organ is the harvesting of small amounts of tissue from the future recipient of the tissue-engineered organ.
             History.
             In 1858, Rudolf Carl Virchow (1821-1902) described his conceptions about cell formation with the now famous words, "Omnis cellula e cellula. "Verbally Expressing that cells arise from pre-subsisting cells, conflating Matthias Jakob Schleiden and Theodor Schwann conception of spontaneous cell generation. Virchow presented his conceptions about regeneration verbalizing that tissue regeneration is dependent on cell proliferation. This led research to focus attention toward the more fundamental cellular level. Karl Thiersch endeavored to grow skin cells into granulating wounds.


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