Symptoms of Pancreatitis include steady, sudden-onset abdominal pain radiating to the back and epigastric tenderness, fever, and tachycardia. Associated with nausea and vomiting. A history of gallstones or alcohol intake is often present. Initial treatment includes IV fluids and correction of electrolyte abnormalities, analgesia, and glucose control. The main goal is to prevent complications, which may include coagulopathy, respiratory distress, ascites, bowel obstructions, sepsis, and renal failure.
Lipase and Amylase are the two hallmark lab tests for pancreatitis. Lipase is more sensitive for detecting nonalcoholic and alcoholic pancreatitis. The lipase is considered more diagnostic. Lipase is more sensitive and specific than amylase and is therefore preferred and considered more diagnostic. Its use can also be helpful in patients presenting with suggestive symptoms of pancreatitis and normal amylase. Levels start rising 4 to 8 hours after the onset of pain, peak at 24 hours, and last for 8 to 14 days. Patients with alcoholic pancreatitis have higher levels of lipase than those with gallstone pancreatitis. Urinary trypsinogen -2 rapid dip stick was found in a study by Yeng-Ting Chen to be as effective as lipase in the initial diagnosing phase. Serous factors of trypsinogen has a sensitivity and specificity of >94% and is sometimes considered a better screening test than amylase. .
Other diagnostics may include some but not all of the procedures below:.
CBC- WBC infection, H/H for hemorrhage.
CMP " electrolytes, dehydration, renal status, glucose.
CRP " useful to determine severity and if necrosis.
Stool samples measuring fat.
Abdominal xrays to r/o obstruction or other bowel issues.
CT- for gallstones and inflammation.
MRCP allows better visualization than a CT of common bile duct stones and the pancreatic duct and no IV for contrast is needed.
ERCP - identifies stones and allows their retrieval during the same intervention; can identify duct defects and strictures.
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In Trinidad, there is a common complication of acute pancreatitis where there are two cases (Waterman 1938). At the laparotomy there is pancreatic psuedocysts and Hemorrhagic pancreatitis which follow the stings. Patients had hyperamylasaemia excluding the abdominal pain confirming painless pancreatitis in acute states. Death however, occurred with ailments apart from pancreatitis (Bartholomew 1970). ... In Trinidad, Tityus Trinitatis is mostly the cause of pancreatitis even though its venom is not recognized widely....
Four hours later a doctor came in and told me the problem was "Inflammation of the pancreas, or the medical term, Pancreatitis." ... This horrible experience has extensively tested my faith in doctors and in myself during this horrifying experience of acute re-occurring pancreatitis. ...
This is associated with a variety of urological complications, reflux graft pancreatitis, and hematuria. ... The pancreas is evaluated for parenchymal echogenicity, location and orientation Measurements of the size of the graft should be made to establish a baseline for detection of enlargement that is associated with acute rejection and acute pancreatitis Search for peripancreatic fluid collections Arterial and venous blood flow is evaluated Normal Pancreas Transplant In the immediate postoperative period, the transplant commonly shows focal abnormalities related to handling and surgical tr...
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If the infant is left untreated, the physical ramification of the acute leukaemia (leucine poisoning) and ketonuria (keto acid poisoning) can cause vomiting, dehydration, lethargy, seizures, pancreatitis, coma, and eventually death. ...
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But other problems such as liver disease, heart disease, certain forms of cancer, and pancreatitis often develop more gradually and may become evident only after long-term heavy drinking. ... Long-term heavy drinking can lead to pancreatitis, or inflammation of the pancreas. ...