Frank is a down-on-your-luck widower who does not believe the body is a temple.
He eats badly, is hygienically challenged, and abstains from exercise. His only saving .
grace is his daughter Shane, who tries everything to get her dad to stay healthy. However, .
what goes on inside Frank's body is a whole other story. The "City of Frank" is a busy .
metropolis where one white blood cell cop, Osmosis Jones, teams up with the rookie cold .
tablet Drixenol and tries hard to keep the peace. Yet he runs up against Mayor .
Phlegmming again and again, who feels "a fat Frank is a happy Frank." When a mysterious, .
evil virus named Thrax invades the "City of Frank" and threatens to kill R-O, Frank, Jones, .
along with the help of Drixenol, must convince everyone that something really terrible is .
about to happen. Meanwhile, in the outside world, a doctor is trying to discover what the .
matter is with Frank. The five wrong things that Frank did that made him physically sick .
are: he at the egg that was in the monkey's mouth, he ate the fried chicken leg, he does not .
wash (not hygienic), he ate the oyster from the science project, he drank beer, and he ate the .
peanut candy.
Mayor Phlegmming portrayed the brain and he said that it is good for Frank to eat .
unhealthy. By saying that the Mayor wants to win the campaign and by doing that he .
thought if he made Frank happy "letting him eat whatever he wants to eat and being .
unhealthy, that is how he would get his votes. On the other hand, there is Tom Colonic, .
who is young and only wants what is healthy for Frank. For example, like his "Colonic Ad .
Bowels.? Tom Colonic is a funny name because "Colonic?is the adjective of "colon.? .
Colon means the part of the large intestine extending from the appendix to the rectum. In .
Tom Colonic's campaign, he made a tape called "Colonic Ad Bowels?and bowels mean .
the intestines or to pass waste matter from the large intestine.