A comparison between human and mouse showed that transcription factor binding sites are considerably less conserved than protein-coding sequences (69). ... Nonetheless, we found that functional target genes of these two factors were enriched for shared binding events. ... The loss of the majority of binding events can be explained by disruption of the transcription factor's binding motif as a result of changes in the DNA sequence, whereas species-specific gains of binding events are frequently found in novel sequences that cannot be aligned with the other species (10). Not all transcript...

• Word Count: 728
• Approx Pages: 3
• Grade Level: Graduate

Beginning Teachers in Singapore are increasingly confronted by various challenges in implementing novel introductions and amendments in the education system; one of which is the Character and Citizenship Education (CCE). Another challenge facing beginning teachers arises from working with the first point of contact with the external community; the parents (Boon, 2011) - the most important stakeholders in education outside the domain of the school's administration. ... Beginning teachers will have to undertake the responsibility of evaluating the spectrum of factors that contribute to the...

• Word Count: 1604
• Approx Pages: 6
• Has Bibliography
• Grade Level: Graduate