This has been demonstrated in a number of studies, for example with the antimalarial drug chloroquine or the radical scavenger superoxide dismutase (Oussoren et al., 2000). ... Other examples are the reduction of haemolytic effects of drugs by liposome encapsulation and the protection against local irritation upon intradermal, subcutaneous or intramuscular injection of a tissue-irritating drug (Kadir et al., 1999). ... The method that was used is related to the immunoliposomes that are interrelating with a cell surface receptor that is endocytosed, leading to immunoliposome internalisation upo...

• Word Count: 650
• Approx Pages: 3
• Grade Level: Graduate

Gleevec was originally derived from a lead compound detected in a screening for inhibitors of protein kinase C (Capdeville et al.: 2002). ... The TK mutants with drug resisting capabilities are able to undergo constitutive activation of signaling pathways, promote an increased efflux of the drug, and even generate plasma proteins that bind to the drug to decrease its concentration (Krause et al: 2005). ... Another article presents a more insightful current clinical investigation of monoclonal antibody drug use with BC8, a CD45-targeting monoclonal antibody for hematological malignancies (Vache...

• Word Count: 1146
• Approx Pages: 5
• Has Bibliography
• Grade Level: Graduate

Social interchanges, an "interpersonal interaction in which two individuals behave in ways that contribute to each others' general patterns of behavior" (Farmer, et al., 2012, p.151) have two forms of synchronized behavior: reciprocity and complementarity in which two individuals respond with similar behaviors, and in which the behavior of one is necessary for the behavior of the other, respectively. ... They "elicit and constrain the interactions and opportunities youth are afforded in the school context" (Farmer, et al., 2012, p. 154). ... A tiered intervention frame...

• Word Count: 755
• Approx Pages: 3
• Has Bibliography
• Grade Level: Graduate

Reflecting the weakening of the agency logic and the emergence of a stakeholder orientation, the establishment of "Chief Sustainability Officer" role is regarded as a milestone in the evolution of the interpretation and assessment of CSR, shifting it from an issue of "philanthropy" to a core strategic issue and a potential driver of innovation and long-term performance (Lubin & Esty, 2010; Kiron, Kruschwitz, Haanaes et al., 2012).So far, in stead of considering CSR investment as the "charitable giving", investors gradually re-considering CSR from the stakeholders&...

• Word Count: 1081
• Approx Pages: 4
• Grade Level: Graduate

For example, another study, taken just a few years later, describes the poisoning of many Bangladesh citizens because of what is known as Manganese, which is a transition metal and also, in many cases, a deadly neurotoxin (Wasserman et al, 2006). There are also claims that this metal can also cause damage when drunk from water, the same way that arsenic can, further increasing the danger of poisoning in the country (Wasserman et al, 2006). ... For example, one study cites stillbirth as one of the many indirect causes of the arsenic contamination in Bangladesh, stating that ingesting this arsen...

• Word Count: 1023
• Approx Pages: 4
• Has Bibliography
• Grade Level: Graduate

Globalization is a phenomenon that started in a primeval form in the last half of the 20th century, and has briskly and steadily advanced in recent times, due to rapid technological advancements. International boundaries have become almost non-existent as multinationals are using strategies to expan...

• Word Count: 821
• Approx Pages: 3
• Has Bibliography
• Grade Level: Graduate

Online travel wholesaler Priceline.com, has numerous options with respect to assessing the efficacy of its marketing programs and determining its return on investment (ROI) for such expenditures. This section shall analyze the types of metrics available for measuring marketing program efficacy and/...

• Word Count: 729
• Approx Pages: 3
• Has Bibliography
• Grade Level: Graduate

In 1945, Pace et al published their first paper called "The Effect of Transfusions of Red Blood Cells on the Hypoxia Tolerance of Normal Men" which was followed by another in 1947, "The increase in Hypoxia Tolerance of Normal Men Accompanying the Polycythemia Induced by Transfusion. ...

• Word Count: 800
• Approx Pages: 3
• Grade Level: Graduate

The other article by Tucker, Shenk, Lernetti et al. and Neil summarizes some of the theoretical challenges that applies to Human Behavioral Ecology, and ways in which evolutionary anthropologists can contribute to solving tough world issues. ...

• Word Count: 708
• Approx Pages: 3
• Has Bibliography
• Grade Level: Graduate

The well-used term "identity crisis," originates from Erik Erikson's fifth stage, identity versus confusion, in his eight stages of epigenetic personality development. Presumably occurring during late adolescence, the successful resolution of this crisis develops a healthy identity and a strong s...

• Word Count: 784
• Approx Pages: 3
• Has Bibliography
• Grade Level: Graduate

As the Internet has become an integral tool of businesses, company policies on Internet usage have become as common as policies regarding vacation days or sexual harassment. A 2005 study by the American Management Association and ePolicy Institute found that 76% of companies monitor employees' use o...

• Word Count: 1243
• Approx Pages: 5
• Grade Level: Graduate

The visual cliff is an experiment designed by Eleanor Gibson and Richard Walk (1960) to study the presence of depth perception in children, Campos et al (2000) suggest that children with more crawling experience regardless of when they start crawling refuse to cross the visual cliff earlier suggesting that their depth perception develops quicker than children who are not afforded the opportunity for ample crawling. ...

• Word Count: 958
• Approx Pages: 4
• Grade Level: Graduate

(Kendler et al, 1995) However from these studies, psychologists have noticed four major contributors to making it more likely to gain a phobia, which include: your current age, your gender, family fears, as well as if you suffered a traumatic incident. ...

• Word Count: 1202
• Approx Pages: 5
• Has Bibliography
• Grade Level: Graduate

The recent rise of new forms of media and the modern changes in the world have driven individuals to invest less time watching TV, listening to the radio and reading magazines and books (Gardner et al. 2009); lately, youthful demographics have progressively moved their hobbies to alternative types of entertainment. ...

• Word Count: 1065
• Approx Pages: 4
• Has Bibliography
• Grade Level: Graduate

This research exercise will be examining a case study which involves Indigenous individuals getting shoot in King Cross area of Sydney and also this research will be highlighting how this situation could have been prevented through the practice of preventative strategies. This accident occurred on S...

• Word Count: 1044
• Approx Pages: 4
• Has Bibliography
• Grade Level: Graduate