1. Maeder, Thomas. Sweet medicines. Scientific American. Jul
However, cells not only consist of genes and proteins, but also of carbohydrates (sugars) and lipids (fats). ... After wounding or infection, endothelial cells that line blood vessels begin to display large numbers of carbohydrate-binding proteins called selectins. Selectins bind loosely to specific carbohydrates on the surface of white blood cells of the immune system. ... Substances that interfere with the contact between carbohydrates and selectins are now under development as anti-inflammatory drugs. ... Serious problems confront the development of carbohydrate-based drugs, especially one...
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