1. Tay-Sachs disease
The baby then becomes blind, and dies, usually before its 5th year (Seely et al, 1992). ... This mutation is also prevelant in the southwest Louisiana Cajun population. ... The other mutation was of a form of Tay-Sachs disease found in the French-Canadian populations. ... This mutation was identified in one Moroccan patient and three unrelated heterozygous carriers( Drucker et al, 1992). ... They had 11 offspring, 5 of whom must have been heterozygous for the mutation, because they had carrier descendants through a total of 14 descendant lines(DeBruekeleer et al, 1992). ...
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- Grade Level: High School