1. Tay-Sachs disease
The baby then becomes blind, and dies, usually before its 5th year (Seely et al, 1992). ... B-hexosaminidase A is composed of two amino acid chains, the alpha and the beta chain(Navon et al, 1989). ... All forms of Tay-Sachs disease are caused by mutations in the alpha chain of the enzyme(Navon et al, 1989). ... This results in defective splicing of the mRNA(Arpaia et al, 1988). ... Jews with Austrian ancestry had a frequency of 1 in 9(Petersen et al, 1983). ...
- Word Count: 1263
- Approx Pages: 5
- Grade Level: High School